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Anti-Leukotriene A4 Hydrolase Antibody (3C202)

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Catalog No. TMAH-00708
Alias leukotriene A4 hydrolase, LAT4

Anti-Leukotriene A4 Hydrolase Antibody (3C202) is an antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (3C202) can be used in ELISA, WB.

Anti-Leukotriene A4 Hydrolase Antibody (3C202)

Anti-Leukotriene A4 Hydrolase Antibody (3C202)

😃Good
Catalog No. TMAH-00708Alias leukotriene A4 hydrolase, LAT4
Anti-Leukotriene A4 Hydrolase Antibody (3C202) is an antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (3C202) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Monoclonal

Application: ELISA, WB

Reactivity: Human, Mouse
Aliasleukotriene A4 hydrolase, LAT4
Ig Type
Rabbit IgG
Clone
3C202
Reactivity
Human, Mouse
Verified Activity
Western Blot
-Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, 293T whole cell lysate, PC-3 whole cell lysate, Mouse Brain whole cell lysate
-All lanes: LTA4H antibody at 1:1000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 70, 60, 58, 67 kDa
-Observed band size: 70 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:5000.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundBifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the proinflammatory mediator leukotriene B4 (LTB4). Has also aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides. In addition to its proinflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL). Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human LTA4H
Antigen Species
Human
Gene ID
4048
Uniprot ID
Biology Area
Cancer, Immunology, Metabolism
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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