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Anti-SSTR2 Antibody (8O74)
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Catalog No. TMAH-01134
Alias somatostatin receptor 2
Anti-SSTR2 Antibody (8O74) is an antibody targeting SSTR2. Anti-SSTR2 Antibody (8O74) can be used in ELISA,FC.
Anti-SSTR2 Antibody (8O74)
Anti-SSTR2 Antibody (8O74)
😃Good
Catalog No. TMAH-01134Alias somatostatin receptor 2
Anti-SSTR2 Antibody (8O74) is an antibody targeting SSTR2. Anti-SSTR2 Antibody (8O74) can be used in ELISA,FC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA, FC Reactivity: Human |
| Alias | somatostatin receptor 2 |
| Ig Type | Human IgG1 |
| Clone | 8O74 |
| Reactivity | Human |
| Verified Activity | 1. Untransfected CT26 cells surface (green line) and transfected Human SSTR2 CT26 stable cells surface (red line) were stained with anti-SSTR2 recombinant antibody (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 2. The Binding Activity of Huamn SSTR2 with Anti-SSTR2 recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SSTR2 at 10 μg/mL can bind Anti-SSTR2 recombinant antibody (TMAH-01134), the EC50 is 58.13-81.28 ng/mL. |
| Application | ELISA, FC |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SSTR2 Protein |
| Antigen Species | Human |
| Gene ID | 6752 |
| Uniprot ID | |
| Biology Area | Immunology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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