TROP-2 Protein, Human, Recombinant (hFc) V2

Catalog No. TMPY-06972U

TROP-2 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is P09758.

TROP-2 Protein, Human, Recombinant (hFc) V2

Catalog No. TMPY-06972U

TROP-2 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is P09758.

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Biological Activity	Immobilized Human TROP-2, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TROP-2 Antibody, hFc Tag with the EC50 of 11.3 ng/ml determined by ELISA.
Description	TROP-2 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is P09758.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P09758
Synonyms	tumor-associated calcium signal transducer 2,TROP-2,TROP2,TACD2,M1S1,GP50,GA733-1,GA7331,EGP-1,EGP1
Construction	His27-Thr274
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	54.6 kDa (Predicted); 60-70 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.