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Synonyms: Protein MER6, OA-3, OA3, OA 3, MER-6, MER6, MER 6, Leukocyte surface antigen CD47, Leukocyte Surface Antigen CD47, Integrin-associated protein, Integrin-Associated Protein, IAP, CD47 molecule, CD-47, CD47, CD 47, Antigenic surface determinant protein OA3, Antigenic Surface Determinant Protein OA3


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $189 | 7-10 days | 7-10 days | |
| 20 µg | $293 | 7-10 days | 7-10 days | |
| 50 µg | $548 | 7-10 days | 7-10 days | |
| 100 µg | $873 | 7-10 days | 7-10 days | |
| 200 µg | $1,390 | 7-10 days | 7-10 days | |
| 500 µg | $2,580 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized FITC-Labeled Human CD47, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human SIRP alpha, hFc Tag with the EC50 of 77.4 ng/ml determined by ELISA (QC Test). |
| Description | CD47 Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 Cells. The accession number is Q08722-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q08722-1 |
| Construction | Gln19-Pro139 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | Protein MER6, OA-3, OA3, OA 3, MER-6, MER6, MER 6, Leukocyte surface antigen CD47, Leukocyte Surface Antigen CD47, Integrin-associated protein, Integrin-Associated Protein, IAP, CD47 molecule, CD-47, CD47, CD 47, Antigenic surface determinant protein OA3, Antigenic Surface Determinant Protein OA3 |
| Research Background | CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers. |
| Molecular Weight | 14.5 kDa (Predicted); 45-55 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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