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GDNF Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P39905-1.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $124 | 7-10 days | 7-10 days | |
| 10 μg | $186 | 7-10 days | 7-10 days | |
| 20 μg | $279 | 7-10 days | 7-10 days | |
| 50 μg | $570 | 7-10 days | 7-10 days | |
| 100 μg | $983 | 7-10 days | 7-10 days |
| Biological Activity | Immobilized Human GDNF, No Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFR alpha 1, His Tag with the EC50 of 5.0 ng/ml determined by ELISA. |
| Description | GDNF Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P39905-1. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P39905-1 |
| Synonyms | HSCR3,HFB1-GDNF,glial cell derived neurotrophic factor,ATF2,ATF1 |
| Construction | Ser78-Ile211 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Molecular Weight | 15.06 kDa (Predicted and reducing conditions) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Glial cell line-derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons. |
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