Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-TrkA Antibody (8K93)

(Synonyms: neurotrophic tyrosine kinase, receptor, type 1) Copy Product Info
🥰Excellent

Synonyms: neurotrophic tyrosine kinase, receptor, type 1

Catalog No. TMAC-04131 Copy Product Info
🥰Excellent
Anti-TrkA Antibody (8K93) is a Rabbit antibody targeting TrkA. Anti-TrkA Antibody (8K93) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-TrkA Antibody
(8K93)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-TrkA Antibody (8K93) is a Rabbit antibody targeting TrkA. Anti-TrkA Antibody (8K93) can be used in FCM,ICC/IF,IHC,IP,WB.
Synonymsneurotrophic tyrosine kinase, receptor, type 1
Ig Type
IgG
Clone
8K93
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning. In the adult nervous system, the Trk receptors regulate synaptic strength and plasticity. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions, and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA. TrkA is activated in many malignancies including breast, ovarian, prostate, and thyroid carcinomas. Research studies suggest that expression of TrkA in neuroblastomas may be a good prognostic marker as TrkA signals growth arrest and differentiation of cells originating from the neural crest.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 145 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator
Related Tags: Anti-TrkA Antibody (8K93) molecular weight