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Anti-TYMS Antibody (8R369)
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Catalog No. TMAC-04037
Alias TSase, TS, Thymidylate synthase, EC 2.1.1.45
Anti-TYMS Antibody (8R369) is a Rabbit antibody targeting TYMS. Anti-TYMS Antibody (8R369) can be used in WB,IHC,IP,FCM.
Anti-TYMS Antibody (8R369)
Anti-TYMS Antibody (8R369)
😃Good
Catalog No. TMAC-04037Alias TSase, TS, Thymidylate synthase, EC 2.1.1.45
Anti-TYMS Antibody (8R369) is a Rabbit antibody targeting TYMS. Anti-TYMS Antibody (8R369) can be used in WB,IHC,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-TYMS Antibody (8R369) is a Rabbit antibody targeting TYMS. Anti-TYMS Antibody (8R369) can be used in WB,IHC,IP,FCM. |
| Synonyms | TSase, TS, Thymidylate synthase, EC 2.1.1.45 |
| Ig Type | IgG |
| Clone | 8R369 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Thymidylate Synthase on different cell lysate using anti-Thymidylate Synthase antibody at 1/1,000 dilution. Positive control: Lane1: Hela, Lane2: Jurkat, Lane3: Raji, Lane4: Mouse testes, Lane5: Mouse brain, Lane6: Mouse spleen. 2. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Thymidylate Synthase antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Thymidylate Synthase antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded rat bone tissue using anti-Thymidylate Synthase antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of Hela cells with Thymidylate Synthase antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Thymidylate synthase (TS), also designated TYMS, TMS, TSase and HsT422, uses 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor in the synthesis of 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor for DNA biosynthesis. TS is an RNA-binding protein that can interact with its own mRNA. The TS/mRNA ribonucleoprotein complex can also associate with a number of other cellular mRNAs, including those corresponding to the p53 tumor suppressor gene and the Myc family of transcription factors. Inhibition of DNA replication and cell death resulting from thymidine depletion occurs when TS enzyme activity is inhibited with substrate or cofactor analogs, making the TS enzyme an important target for chemotherapy. Cancer cells are sensitive to thymidine depletion, as they multiply rapidly. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 36 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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