IL-5 Protein, Mouse, Recombinant (HEK293, His)

Name: IL-5 Protein, Mouse, Recombinant (HEK293, His)
Brand: TargetMol
SKU: TMPY-02554U
Rating: 4.5 (1 reviews)

(Synonyms: Il-5) Copy Product Info

Synonyms: Il-5

Catalog No. TMPY-02554U Copy Product Info

IL-5 Protein, Mouse, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P04401.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$43	7-10 days	7-10 days
10 µg	$66	7-10 days	7-10 days
20 µg	$106	7-10 days	7-10 days
50 µg	$222	7-10 days	7-10 days
100 µg	$397	7-10 days	7-10 days
200 µg	$700	7-10 days	7-10 days
500 µg	$1,480	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells.The ED50 for this effect is 115.5 pg/mL.
Description	IL-5 Protein, Mouse, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P04401.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P04401
Construction	Met21-Gly133
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Il-5
Research Background	IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.

Chemical Properties

Molecular Weight

13.9 kDa (Predicted); 14-26 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.