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Anti-eIF4E Antibody (2V139)

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Catalog No. TMAB-05518

Anti-eIF4E Antibody (2V139) is a Rabbit antibody targeting eIF4E. Anti-eIF4E Antibody (2V139) can be used in WB,IHC-P,IHC-Fr,IF,IP,FCM.

Anti-eIF4E Antibody (2V139)

Anti-eIF4E Antibody (2V139)

😃Good
Catalog No. TMAB-05518
Anti-eIF4E Antibody (2V139) is a Rabbit antibody targeting eIF4E. Anti-eIF4E Antibody (2V139) can be used in WB,IHC-P,IHC-Fr,IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-eIF4E Antibody (2V139) is a Rabbit antibody targeting eIF4E. Anti-eIF4E Antibody (2V139) can be used in WB,IHC-P,IHC-Fr,IF,IP,FCM.
Ig Type
IgG
Clone
2V139
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, P-body.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundActs in the cytoplasm to initiate and regulate protein synthesis and is required in the nucleus for export of a subset of mRNAs from the nucleus to the cytoplasm which promotes processes such as RNA capping, processing and splicing.
Antigen Details
Immunogen
A synthesized peptide: human eIF4E
Antigen Species
Human
Gene Name
EIF4E
Gene ID
Protein Name
Eukaryotic translation initiation factor 4E
Uniprot ID
Function
Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Chemical Properties
Molecular WeightTheoretical: 25 kDa. Actual: 30 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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