BMPRIB Protein, Human, Recombinant (GST)

Name: BMPRIB Protein, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPC-00078
Rating: 4.5 (1 reviews)

(Synonyms: CDw293, Bone morphogenetic protein receptor type-1B, BMPR-1B, BMPR1B, BMP type-1B receptor) Copy Product Info

Synonyms: CDw293, Bone morphogenetic protein receptor type-1B, BMPR-1B, BMPR1B, BMP type-1B receptor

Catalog No. TMPC-00078 Copy Product Info

BMPRIB Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is O00238.

Pack Size	Price	USA Stock	Global Stock	Quantity
10 µg	$1,390	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Representative specific activity data for BMPRIB were obtained using different assay formats: - 19 nmol/min/mg, determined by radioactive kinase assay - 20 nmol/min/mg, determined by ADP-Glo kinase assay Different lots may be tested using different assay methods; therefore, values obtained using different assay formats are not directly comparable.
Description	BMPRIB Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is O00238.
Species	Human
Expression System	Baculovirus-Insect Cells
Tag	N-GST
Accession Number	O00238
Construction	Recombinant human ALK6 (BMPR1B) (149-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Protein Purity	>85% as determined by SDS-PAGE.
Formulation	Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Synonyms	CDw293, Bone morphogenetic protein receptor type-1B, BMPR-1B, BMPR1B, BMP type-1B receptor
Research Background	BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective transducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.

Chemical Properties

Molecular Weight

~68 kDa

Storage & Solubility Information

Shipping	Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.