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Anti-DKK1 Antibody (8S801)
(Synonyms: SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1) Copy Product Info
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Synonyms: SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Catalog No. TMAC-01151 Copy Product Info
🥰Excellent
Anti-DKK1 Antibody (8S801) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (8S801) can be used in FCM,ICC/IF,IHC,WB.
Anti-DKK1 Antibody
(8S801)
(8S801)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-DKK1 Antibody (8S801) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (8S801) can be used in FCM,ICC/IF,IHC,WB. |
| Synonyms | SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1 |
| Ig Type | IgG |
| Clone | 8S801 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Wnt genes are a group of well conserved, cysteine-rich secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the seven membrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation, causing the accumulation of b-catenin and subsequent regulation of developmentally significant Wnt |target genes. The Dickkopf family of secreted inhibitors of Wnt signaling ensures proper morphological development by antagonizing different stages of the Wnt cascade. Dkk-1 (Dickkopf-1) acts upstream of b-catenin and dishevelled to inhibit Wnt signaling. Dkk-1 is a 266-amino acid (human), secreted protein that contains a 31-residue N-terminal signal peptide, 2 cysteine rich domains, and a putative carboxy terminal N-glycosylation site. Human Dkk-1 transcripts are abundantly present in fetal kidney, adult placenta and adult prostate. Putative cis regulatory elements upstream of the Dkk-1 start site include p53, Sp1, MyoD, STAT, Oct-1/2, C/EBP-a, C/EBP-b, GATA-1, GATA-2 and GATA-3. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 38 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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