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Anti-PGC1 alpha/beta Antibody (4L458)
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Catalog No. TMAB-10241
Anti-PGC1 alpha/beta Antibody (4L458) is a Rabbit antibody targeting PGC1 alpha/beta. Anti-PGC1 alpha/beta Antibody (4L458) can be used in WB.
Anti-PGC1 alpha/beta Antibody (4L458)
Anti-PGC1 alpha/beta Antibody (4L458)
😃Good
Catalog No. TMAB-10241
Anti-PGC1 alpha/beta Antibody (4L458) is a Rabbit antibody targeting PGC1 alpha/beta. Anti-PGC1 alpha/beta Antibody (4L458) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PGC1 alpha/beta Antibody (4L458) is a Rabbit antibody targeting PGC1 alpha/beta. Anti-PGC1 alpha/beta Antibody (4L458) can be used in WB. |
| Ig Type | IgG |
| Clone | 4L458 |
| Reactivity | Mouse,Rat (predicted:Human) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Heart, skeletal muscle, liver and kidney. Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue. In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Transcriptional coactivator for steroid receptors and nuclear receptors.Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter.Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. |
| Immunogen | A synthesized peptide: human PGC1 alpha |
| Antigen Species | Human |
| Gene Name | PPARGC1A |
| Gene ID | |
| Protein Name | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
| Uniprot ID | |
| Function | Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. |
| Molecular Weight | Theoretical: 91, 113 kDa. Actual: 113 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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