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Anti-MEK5 Antibody (4Y111)
😃Good
Catalog No. TMAB-08737
Anti-MEK5 Antibody (4Y111) is a Rabbit antibody targeting MEK5. Anti-MEK5 Antibody (4Y111) can be used in WB,ICC/IF.
Anti-MEK5 Antibody (4Y111)
Anti-MEK5 Antibody (4Y111)
😃Good
Catalog No. TMAB-08737
Anti-MEK5 Antibody (4Y111) is a Rabbit antibody targeting MEK5. Anti-MEK5 Antibody (4Y111) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MEK5 Antibody (4Y111) is a Rabbit antibody targeting MEK5. Anti-MEK5 Antibody (4Y111) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 4Y111 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed in many adult tissues. Abundant in heart and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM. |
| Immunogen | A synthesized peptide: human MEK5 |
| Antigen Species | Human |
| Gene Name | MAP2K5 |
| Gene ID | |
| Protein Name | Dual specificity mitogen-activated protein kinase kinase 5 |
| Uniprot ID | |
| Function | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis. |
| Molecular Weight | Theoretical: 50 kDa. Actual: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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