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Anti-Adenylate kinase 2 Antibody (4N197)
🥰Excellent
Catalog No. TMAB-02329
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,IHC-P,IHC-Fr,ICC/IF,IF,IP
Reactivity: Human,Mouse,Rat
Anti-Adenylate kinase 2 Antibody (4N197)
Anti-Adenylate kinase 2 Antibody (4N197)
🥰Excellent
Catalog No. TMAB-02329
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,IHC-P,IHC-Fr,ICC/IF,IF,IP
Reactivity: Human,Mouse,Rat
Application: WB,IHC-P,IHC-Fr,ICC/IF,IF,IP
Reactivity: Human,Mouse,Rat
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Adenylate kinase 2 Antibody (4N197) is a Rabbit antibody targeting Adenylate kinase 2. Anti-Adenylate kinase 2 Antibody (4N197) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP. |
| Ig Type | IgG |
| Clone | 4N197 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion intermembrane space. |
| Tissue Specificity | Present in most tissues. Present at high level in heart, liver and kidney, and at low level in brain, skeletal muscle and skin. Present in thrombocytes but not in erythrocytes, which lack mitochondria. Present in all nucleated cell populations from blood, while AK1 is mostly absent. In spleen and lymph nodes, mononuclear cells lack AK1, whereas AK2 is readily detectable. These results indicate that leukocytes may be susceptible to defects caused by the lack of AK2, as they do not express AK1 in sufficient amounts to compensate for the AK2 functional deficits (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Plays a key role in hematopoiesis. |
| Immunogen | A synthesized peptide: human Adenylate kinase 2 |
| Antigen Species | Human |
| Gene Name | AK2 |
| Gene ID | |
| Protein Name | Adenylate kinase 2, mitochondrial |
| Uniprot ID | |
| Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Plays a key role in hematopoiesis. |
| Molecular Weight | Theoretical: 26 kDa. Actual: 26 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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