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Anti-Myosin VIIa Antibody (4I576)
😃Good
Catalog No. TMAB-09185
Anti-Myosin VIIa Antibody (4I576) is a Rabbit antibody targeting Myosin VIIa. Anti-Myosin VIIa Antibody (4I576) can be used in WB.
Anti-Myosin VIIa Antibody (4I576)
Anti-Myosin VIIa Antibody (4I576)
😃Good
Catalog No. TMAB-09185
Anti-Myosin VIIa Antibody (4I576) is a Rabbit antibody targeting Myosin VIIa. Anti-Myosin VIIa Antibody (4I576) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,057 | 7-10 days | 7-10 days | |
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days | |
| 200 μL | $754 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Myosin VIIa Antibody (4I576) is a Rabbit antibody targeting Myosin VIIa. Anti-Myosin VIIa Antibody (4I576) can be used in WB. |
| Ig Type | IgG |
| Clone | 4I576 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm (Probable). Note=In the photoreceptor cells, mainly localized in the inner and base of outer segments as well as in the synaptic ending region. |
| Tissue Specificity | Expressed in the pigment epithelium and the photoreceptor cells of the retina. Also found in kidney, liver, testis, cochlea, lymphocytes. Not expressed in brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle. |
| Immunogen | Recombinant Protein: mouse Myosin VIIa protein |
| Antigen Species | Mouse |
| Gene Name | MYO7A |
| Gene ID | |
| Protein Name | Unconventional myosin-VIIa |
| Function | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa might play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it might maintain the rigidity of stereocilia during the dynamic movements of the bundle. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity. |
| Molecular Weight | Theoretical: 244 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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