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Anti-ZNF348/Kaiso Antibody (8Q66) is a Rabbit antibody targeting ZNF348/Kaiso. Anti-ZNF348/Kaiso Antibody (8Q66) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-ZNF348/Kaiso Antibody (8Q66) is a Rabbit antibody targeting ZNF348/Kaiso. Anti-ZNF348/Kaiso Antibody (8Q66) can be used in WB. |
| Ig Type | IgG |
| Clone | 8Q66 |
| Reactivity | Human,Rat (predicted:Mouse) |
| Application | |
| Recommended Dose | WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Also cytoplasmic in cells grown at high densities. |
| Tissue Specificity | Expressed in vascular endothelium. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. |
| Immunogen | A synthesized peptide: human KAISO |
| Antigen Species | Human |
| Gene Name | ZBTB33 |
| Gene ID | |
| Protein Name | Transcriptional regulator Kaiso |
| Uniprot ID | |
| Function | Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. |
| Molecular Weight | Theoretical: 74 kDa. Actual: 85 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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