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Anti-ZNF348/Kaiso Antibody (8Q66)

Catalog No. TMAB-14368 Copy Product Info
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Anti-ZNF348/Kaiso Antibody (8Q66) is a Rabbit antibody targeting ZNF348/Kaiso. Anti-ZNF348/Kaiso Antibody (8Q66) can be used in WB.

Anti-ZNF348/Kaiso Antibody (8Q66)

Copy Product Info
🥰Excellent
Catalog No. TMAB-14368

Anti-ZNF348/Kaiso Antibody (8Q66) is a Rabbit antibody targeting ZNF348/Kaiso. Anti-ZNF348/Kaiso Antibody (8Q66) can be used in WB.

Anti-ZNF348/Kaiso Antibody
(8Q66)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ZNF348/Kaiso Antibody (8Q66) is a Rabbit antibody targeting ZNF348/Kaiso. Anti-ZNF348/Kaiso Antibody (8Q66) can be used in WB.
Ig Type
IgG
Clone
8Q66
Reactivity
Human,Rat (predicted:Mouse)
Verified Activity
25 ug total protein per lane of various lysates (see on figure) probed with ZNF348/Kaiso monoclonal antibody, unconjugated (TMAB-14368) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Also cytoplasmic in cells grown at high densities.
Tissue SpecificityExpressed in vascular endothelium.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters.
Antigen Details
Immunogen
A synthesized peptide: human KAISO
Antigen Species
Human
Gene Name
ZBTB33
Gene ID
Protein Name
Transcriptional regulator Kaiso
Uniprot ID
Function
Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2.
Chemical Properties
Molecular WeightTheoretical: 74 kDa. Actual: 85 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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