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Anti-AIF1 Antibody (9M864)
😃Good
Catalog No. TMAB-02394
Anti-AIF1 Antibody (9M864) is a Rabbit antibody targeting AIF1. Anti-AIF1 Antibody (9M864) can be used in WB.
Anti-AIF1 Antibody (9M864)
Anti-AIF1 Antibody (9M864)
😃Good
Catalog No. TMAB-02394
Anti-AIF1 Antibody (9M864) is a Rabbit antibody targeting AIF1. Anti-AIF1 Antibody (9M864) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,060 | 7-10 days | 7-10 days | |
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days | |
| 200 μL | $755 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-AIF1 Antibody (9M864) is a Rabbit antibody targeting AIF1. Anti-AIF1 Antibody (9M864) can be used in WB. |
| Ig Type | IgG |
| Clone | 9M864 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
| Tissue Specificity | Detected in T-lymphocytes and peripheral blood mononuclear cells. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic inflammatory processes. AIF1 is expressed by activated monocytes and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. |
| Immunogen | Recombinant Protein: mouse AIF1 protein |
| Antigen Species | Mouse |
| Gene Name | AIF1 |
| Gene ID | |
| Protein Name | Allograft inflammatory factor 1 |
| Uniprot ID | |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Molecular Weight | Theoretical: 16 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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