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Anti-F11R/JAM-A/CD321 Antibody (7T264)

Catalog No. TMAB-05772 Copy Product Info
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Anti-F11R/JAM-A/CD321 Antibody (7T264) is a Rabbit antibody targeting F11R/JAM-A/CD321. Anti-F11R/JAM-A/CD321 Antibody (7T264) can be used in WB.

Anti-F11R/JAM-A/CD321 Antibody (7T264)

Copy Product Info
🥰Excellent
Catalog No. TMAB-05772

Anti-F11R/JAM-A/CD321 Antibody (7T264) is a Rabbit antibody targeting F11R/JAM-A/CD321. Anti-F11R/JAM-A/CD321 Antibody (7T264) can be used in WB.

Anti-F11R/JAM-A/CD321 Antibody
(7T264)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-F11R/JAM-A/CD321 Antibody (7T264) is a Rabbit antibody targeting F11R/JAM-A/CD321. Anti-F11R/JAM-A/CD321 Antibody (7T264) can be used in WB.
Ig Type
IgG
Clone
7T264
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with F11R/JAM-A/CD321 monoclonal antibody, unconjugated (TMAB-05772) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation1xTBS (pH7.4), 1% BSA, 40% Glycerol and 0.02% Proclin300.
Concentration1mg/ml
Research BackgroundJunctional Adhesion Molecule 1 (JAM1) seems to play a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.
Antigen Details
Immunogen
A synthesized peptide: human JAM A
Antigen Species
Human
Gene Name
F11R
Gene ID
Protein Name
Junctional adhesion molecule A
Uniprot ID
Function
Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Chemical Properties
Molecular WeightTheoretical: 30 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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