Cyclin O/CCNO Protein, Human, Recombinant (GST)

Name: Cyclin O/CCNO Protein, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPC-00195
Rating: 4.5 (1 reviews)

(Synonyms: Cyclin-O, CCNO) Copy Product Info

Synonyms: Cyclin-O, CCNO

Catalog No. TMPC-00195 Copy Product Info

Cyclin O/CCNO Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P22674.

Pack Size	Price	USA Stock	Global Stock	Quantity
20 µg	$953	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description	Cyclin O/CCNO Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P22674.
Species	Human
Expression System	Baculovirus-Insect Cells
Tag	N-GST
Accession Number	P22674
Construction	Recombinant full length human Cyclin O was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Protein Purity	>95% as determined by SDS-PAGE.
Formulation	Supplied as sterile 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Synonyms	Cyclin-O, CCNO
Research Background	Cyclin O (encoded by CCNO) is a member of the cyclin family with regulatory functions in ciliogenesis and apoptosis. Homozygous CCNO mutations have been identified in human patients with Reduced Generation of Multiple Motile Cilia (RGMC) and conditional inactivation of Ccno in the mouse recapitulates some of the pathologies associated with the human disease. These include defects in the development of motile cilia and hydrocephalus. Elevated CCNO expression is closely associated with human gastric cancer (GC) development and that CCNO knockdown could efficiently inhibit the malignant properties of GC cells by inducing cell apoptosis. CCNO could be used as a potential biomarker for prognosis or even as a therapeutic target in human GC.

Chemical Properties

Molecular Weight

~69 kDa

Storage & Solubility Information

Shipping	Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

You can also refer to dose conversion for different animals. More Dose Conversion

Related Tags: Cyclin O/CCNO Protein, Human, Recombinant (GST) chemical structure | Cyclin O/CCNO Protein, Human, Recombinant (GST) molecular weight