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Anti-B7-H3/CD276 Antibody (5R934)

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Catalog No. TMAB-02999

Anti-B7-H3/CD276 Antibody (5R934) is a Rabbit antibody targeting B7-H3/CD276. Anti-B7-H3/CD276 Antibody (5R934) can be used in WB,IP,FCM,IHC-P,IHC-Fr,IF,ICC/IF.

Anti-B7-H3/CD276 Antibody (5R934)

Anti-B7-H3/CD276 Antibody (5R934)

😃Good
Catalog No. TMAB-02999
Anti-B7-H3/CD276 Antibody (5R934) is a Rabbit antibody targeting B7-H3/CD276. Anti-B7-H3/CD276 Antibody (5R934) can be used in WB,IP,FCM,IHC-P,IHC-Fr,IF,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-B7-H3/CD276 Antibody (5R934) is a Rabbit antibody targeting B7-H3/CD276. Anti-B7-H3/CD276 Antibody (5R934) can be used in WB,IP,FCM,IHC-P,IHC-Fr,IF,ICC/IF.
Ig Type
IgG
Clone
5R934
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IP: 1:25-100; FCM: 1:50-100; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein (Probable).
Tissue SpecificityUbiquitous but not detectable in peripheral blood lymphocytes or granulocytes. Weakly expressed in resting monocytes. Expressed in dendritic cells derived from monocytes. Expressed in epithelial cells of sinonasal tissue. Expressed in extravillous trophoblast cells and Hofbauer cells of the first trimester placenta and term placenta.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMay participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces.
Antigen Details
Immunogen
A synthesized peptide: human CD276
Antigen Species
Human
Gene Name
CD276
Gene ID
Protein Name
CD276 antigen
Uniprot ID
Function
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Chemical Properties
Molecular WeightTheoretical: 57 kDa. Actual: 100 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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