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Anti-p53BP1 Antibody (9E596)

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Catalog No. TMAB-09884

Anti-p53BP1 Antibody (9E596) is a Rabbit antibody targeting p53BP1. Anti-p53BP1 Antibody (9E596) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.

Anti-p53BP1 Antibody (9E596)

Anti-p53BP1 Antibody (9E596)

😃Good
Catalog No. TMAB-09884
Anti-p53BP1 Antibody (9E596) is a Rabbit antibody targeting p53BP1. Anti-p53BP1 Antibody (9E596) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-p53BP1 Antibody (9E596) is a Rabbit antibody targeting p53BP1. Anti-p53BP1 Antibody (9E596) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
Clone
9E596
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome; centromere; kinetochore. Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. Methylation of histone H4 at 'Lys-20' is required for efficient localization to double strand breaks.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPlays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1.
Antigen Details
Immunogen
A synthesized peptide: human TP53BP1
Antigen Species
Human
Gene Name
TP53BP1
Gene ID
Protein Name
TP53-binding protein 1
Uniprot ID
Function
May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
Chemical Properties
Molecular WeightTheoretical: 214 kDa. Actual: 450 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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