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Anti-eIF4EBP1 Antibody (6H724)
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Catalog No. TMAB-05521
Anti-eIF4EBP1 Antibody (6H724) is a Rabbit antibody targeting eIF4EBP1. Anti-eIF4EBP1 Antibody (6H724) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Anti-eIF4EBP1 Antibody (6H724)
Anti-eIF4EBP1 Antibody (6H724)
😃Good
Catalog No. TMAB-05521
Anti-eIF4EBP1 Antibody (6H724) is a Rabbit antibody targeting eIF4EBP1. Anti-eIF4EBP1 Antibody (6H724) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-eIF4EBP1 Antibody (6H724) is a Rabbit antibody targeting eIF4EBP1. Anti-eIF4EBP1 Antibody (6H724) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM. |
| Ig Type | IgG |
| Clone | 6H724 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Lung and testis. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. |
| Immunogen | A synthesized peptide: human 4E BP1 |
| Antigen Species | Human |
| Gene Name | EIF4EBP1 |
| Gene ID | |
| Protein Name | Eukaryotic translation initiation factor 4E-binding protein 1 |
| Uniprot ID | |
| Function | Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. |
| Molecular Weight | Theoretical: 13 kDa. Actual: 18 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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