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Anti-eIF4EBP1 Antibody (6H724)

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Catalog No. TMAB-05521 Copy Product Info
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Anti-eIF4EBP1 Antibody (6H724) is a Rabbit antibody targeting eIF4EBP1. Anti-eIF4EBP1 Antibody (6H724) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Anti-eIF4EBP1 Antibody
(6H724)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-eIF4EBP1 Antibody (6H724) is a Rabbit antibody targeting eIF4EBP1. Anti-eIF4EBP1 Antibody (6H724) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
Clone
6H724
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityLung and testis.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundRepressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Antigen Details
Immunogen
A synthesized peptide: human 4E BP1
Antigen Species
Human
Gene Name
EIF4EBP1
Gene ID
Protein Name
Eukaryotic translation initiation factor 4E-binding protein 1
Uniprot ID
Function
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Chemical Properties
Molecular WeightTheoretical: 13 kDa. Actual: 13-16 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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