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Anti-IFN gamma Antibody (2N992)

😃Good
Catalog No. TMAY-02015
Alias interferon, γ, interferon, gamma, IFN γ

Anti-IFN gamma Antibody (2N992) is a Mouse antibody targeting IFN gamma. Anti-IFN gamma Antibody (2N992) can be used in WB.

Anti-IFN gamma Antibody (2N992)

Anti-IFN gamma Antibody (2N992)

😃Good
Catalog No. TMAY-02015Alias interferon, γ, interferon, gamma, IFN γ
Anti-IFN gamma Antibody (2N992) is a Mouse antibody targeting IFN gamma. Anti-IFN gamma Antibody (2N992) can be used in WB.
Pack SizePriceAvailabilityQuantity
20 μL$70 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IFN gamma Antibody (2N992) is a Mouse antibody targeting IFN gamma. Anti-IFN gamma Antibody (2N992) can be used in WB.
Aliasinterferon, γ, interferon, gamma, IFN γ
Ig Type
Monoclonal Mouse IgG1
Clone
2N992
Reactivity
Human
Verified Activity
Anti-IFN-gamma mouse monoclonal antibody at 1:500 dilution.

-Lane A: Jurkat Whole Cell Lysate.

-Lane B: Daudi Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Rabbit Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution.

-Developed using the ECL technique.

-Performed under reducing conditions.

-Predicted band size:19 kDa.

-Observed band size:19 kDa
Application
WB
Recommended Dose
WB: 1:500-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Interferon Gamma Protein (TMPY-01714)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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