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Anti-ADGRE1 Antibody (1T88) is a Rabbit antibody targeting ADGRE1. Anti-ADGRE1 Antibody (1T88) can be used in FCM,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,057 | 7-10 days | 7-10 days | |
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days | |
| 200 μL | $754 | 7-10 days | 7-10 days |
| Description | Anti-ADGRE1 Antibody (1T88) is a Rabbit antibody targeting ADGRE1. Anti-ADGRE1 Antibody (1T88) can be used in FCM,WB. |
| Ig Type | IgG |
| Clone | 1T88 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1μg/Test; WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | Wide expression; increased levels in peripheral blood mononuclear cells. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages. |
| Immunogen | Recombinant Protein: human ADGRE1 |
| Antigen Species | Human |
| Gene Name | ADGRE1 |
| Gene ID | |
| Protein Name | Adhesion G protein-coupled receptor E1 |
| Uniprot ID | |
| Function | Could be involved in cell-cell interactions. |
| Molecular Weight | Theoretical: 95 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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