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Anti-HLTF Antibody (1B226)

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Catalog No. TMAB-07173 Copy Product Info
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Anti-HLTF Antibody (1B226) is a Rabbit antibody targeting . Anti-HLTF Antibody (1B226) can be used in WB,FCM.
Anti-HLTF Antibody
(1B226)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HLTF Antibody (1B226) is a Rabbit antibody targeting . Anti-HLTF Antibody (1B226) can be used in WB,FCM.
Ig Type
IgG
Clone
1B226
Reactivity
Human
Application
Recommended Dose
WB=1:500-2000,FCM=1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityExpressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundHas both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity).
Antigen Details
Immunogen
A synthesized peptide: human HLTF
Antigen Species
Human
Gene Name
HLTF
Gene ID
Protein Name
Helicase-like transcription factor
Uniprot ID
Function
Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Chemical Properties
Molecular WeightTheoretical: 114 kDa. Actual: 130 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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