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Anti-MyD88 Antibody (5D30)

😃Good
Catalog No. TMAB-09142

Anti-MyD88 Antibody (5D30) is a Rabbit antibody targeting MyD88. Anti-MyD88 Antibody (5D30) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.

Anti-MyD88 Antibody (5D30)

Anti-MyD88 Antibody (5D30)

😃Good
Catalog No. TMAB-09142
Anti-MyD88 Antibody (5D30) is a Rabbit antibody targeting MyD88. Anti-MyD88 Antibody (5D30) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MyD88 Antibody (5D30) is a Rabbit antibody targeting MyD88. Anti-MyD88 Antibody (5D30) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
Clone
5D30
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:100-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityUbiquitous.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAdapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Antigen Details
Immunogen
A synthesized peptide: human MyD88
Antigen Species
Human
Gene Name
MYD88
Gene ID
Protein Name
Myeloid differentiation primary response protein MyD88
Uniprot ID
Function
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
Chemical Properties
Molecular WeightTheoretical: 33 kDa. Actual: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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