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Anti-RCHY1 Antibody (1D247)

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Catalog No. TMAB-12167

Anti-RCHY1 Antibody (1D247) is a Rabbit antibody targeting RCHY1. Anti-RCHY1 Antibody (1D247) can be used in WB,ICC/IF,IP.

Anti-RCHY1 Antibody (1D247)

Anti-RCHY1 Antibody (1D247)

Copy Product Info
😃Good
Catalog No. TMAB-12167
Anti-RCHY1 Antibody (1D247) is a Rabbit antibody targeting RCHY1. Anti-RCHY1 Antibody (1D247) can be used in WB,ICC/IF,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-RCHY1 Antibody (1D247) is a Rabbit antibody targeting RCHY1. Anti-RCHY1 Antibody (1D247) can be used in WB,ICC/IF,IP.
Ig Type
IgG
Clone
1D247
Reactivity
Human (predicted:Mouse)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with RCHY1 monoclonal antibody, unconjugated (TMAB-12167) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Nucleus speckle. Cytoplasm.
Tissue SpecificityDetected in testis, liver, kidney and heart.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundE3 ubiquitin-protein ligase that mediates ubiquitination of target proteins, including p53/TP53, TP73, HDAC1 and CDKN1B.
Antigen Details
Immunogen
A synthesized peptide: human RCHY1
Antigen Species
Human
Gene Name
RCHY1
Gene ID
Protein Name
RING finger and CHY zinc finger domain-containing protein 1
Uniprot ID
Function
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Increases AR transcription factor activity. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression.
Chemical Properties
Molecular WeightTheoretical: 30 kDa. Actual: 30 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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