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Anti-TLE1 Antibody (6Y958)
😃Good
Catalog No. TMAB-13568
Anti-TLE1 Antibody (6Y958) is a Rabbit antibody targeting TLE1. Anti-TLE1 Antibody (6Y958) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Anti-TLE1 Antibody (6Y958)
Anti-TLE1 Antibody (6Y958)
😃Good
Catalog No. TMAB-13568
Anti-TLE1 Antibody (6Y958) is a Rabbit antibody targeting TLE1. Anti-TLE1 Antibody (6Y958) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TLE1 Antibody (6Y958) is a Rabbit antibody targeting TLE1. Anti-TLE1 Antibody (6Y958) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Clone | 6Y958 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components. |
| Tissue Specificity | In all tissues examined, mostly in brain, liver and muscle. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. |
| Immunogen | A synthesized peptide: human TLE1 |
| Antigen Species | Human |
| Gene Name | TLE1 |
| Gene ID | |
| Protein Name | Transducin-like enhancer protein 1 |
| Uniprot ID | |
| Function | Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. |
| Molecular Weight | Theoretical: 83 kDa. Actual: 83 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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