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FGF-18 Protein, Mouse, Recombinant

TargetMol | SPR
Catalog No. TMPS-00183

FGF-18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is O89101.

FGF-18 Protein, Mouse, Recombinant

FGF-18 Protein, Mouse, Recombinant

TargetMol | SPR
Catalog No. TMPS-00183
FGF-18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is O89101.
Pack SizePriceAvailabilityQuantity
5 μg$857-10 days
10 μg$1337-10 days
20 μg$2197-10 days
50 μg$3537-10 days
100 μg$5687-10 days
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Product Information

Biological Activity
The ED 50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2.0 × 10^6 IU/mg.
Description
FGF-18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is O89101.
Species
Mouse
Expression System
E. coli
TagTag Free
Accession NumberO89101
Synonyms
zFGF5,Fibroblast growth factor 18,FGF-18
Construction
Glu28-Gly207
Protein Purity
> 95% as determined by SDS-PAGE > 95% as determined by HPLC
Molecular Weight21 kDa (Predicted)
Endotoxin< 1 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a 0.2 µm filtered solution in PBS, pH 7.4, 500 mM NaCl.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Murine FGF-18 is encoded by the FGF18 gene. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles in embryo development. FGF-18–/– mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. In addition, it also has significant roles in lung development and has an anabolic effect on cartilage formation.

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