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FGF-18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is O89101.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $85 | 7-10 days | |
| 10 μg | $133 | 7-10 days | |
| 20 μg | $219 | 7-10 days | |
| 50 μg | $353 | 7-10 days | |
| 100 μg | $568 | 7-10 days |
| Biological Activity | The ED 50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2.0 × 10^6 IU/mg. |
| Description | FGF-18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is O89101. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | O89101 |
| Synonyms | zFGF5,Fibroblast growth factor 18,FGF-18 |
| Construction | Glu28-Gly207 |
| Protein Purity | > 95% as determined by SDS-PAGE > 95% as determined by HPLC |
| Molecular Weight | 21 kDa (Predicted) |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4, 500 mM NaCl. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Murine FGF-18 is encoded by the FGF18 gene. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles in embryo development. FGF-18–/– mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. In addition, it also has significant roles in lung development and has an anabolic effect on cartilage formation. |

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