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Synonyms: TPAR1, TLSF, SDF-1α, SDF-1, SDF1, SCYB12, PBSF, IRH, chemokine (C-X-C motif) ligand 12


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $54 | - | In Stock | |
| 10 µg | $84 | - | In Stock | |
| 20 µg | $136 | 7-10 days | 7-10 days | |
| 50 µg | $248 | 7-10 days | 7-10 days | |
| 100 µg | $397 | 7-10 days | 7-10 days | |
| 200 µg | $673 | 7-10 days | 7-10 days | |
| 500 µg | $1,350 | 7-10 days | 7-10 days |
| Bioactivity | Loaded Recombinant Human CXCR4 (N-Fc) on Pro-A Biosensor, can bind Recombinant Human CXCL12 with an affinity constant of 8.4 uM as determined in BLI assay. (Regularly tested) |
| Description | SDF-1 alpha/CXCL12 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P48061. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P48061 |
| Construction | Lys22-Lys89 |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 0.01 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TPAR1, TLSF, SDF-1α, SDF-1, SDF1, SCYB12, PBSF, IRH, chemokine (C-X-C motif) ligand 12 |
| Research Background | Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface, and can also bind syndecan4. SDF1 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis. It also enhances the survival of myeloid progenitor cells. |
| Molecular Weight | 8 kDa (Predicted); 10 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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