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Anti-CLEC4C Antibody (7F312)
😃Good
Catalog No. TMAH-00284
Alias HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2
Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA.
Anti-CLEC4C Antibody (7F312)
Anti-CLEC4C Antibody (7F312)
😃Good
Catalog No. TMAH-00284Alias HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2
Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA. |
| Synonyms | HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2 |
| Ig Type | Human IgG1 |
| Clone | 7F312 |
| Reactivity | Human |
| Verified Activity | The Binding Activity of CLEC4C with anti-CLEC4C antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLEC4C at 2 μg/mL can bind Anti-CLEC4C recombinant antibody，the EC50 is 7.658-12.99 ng/mL. |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CLEC4C Protein |
| Antigen Species | Human |
| Gene Name | CLEC4C |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Others |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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