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Anti-CLEC4C Antibody (7F312) (Synonyms: HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2)

Catalog No. TMAH-00284 Copy Product Info
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Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA.

Anti-CLEC4C Antibody (7F312)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00284
Synonyms HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2

Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA.

Anti-CLEC4C Antibody
(7F312)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA.
SynonymsHECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2
Ig Type
Human IgG1
Clone
7F312
Reactivity
Human
Verified Activity
The Binding Activity of CLEC4C with anti-CLEC4C antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLEC4C at 2 μg/mL can bind Anti-CLEC4C recombinant antibody,the EC50 is 7.658-12.99 ng/mL.
Application
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type II membrane protein.
Tissue SpecificityExpressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundLectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CLEC4C Protein
Antigen Species
Human
Gene Name
CLEC4C
Gene ID
Uniprot ID
Biology Area
Others
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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