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Anti-ANXA2 Antibody (4Q629) is a Rabbit antibody targeting ANXA2. Anti-ANXA2 Antibody (4Q629) can be used in WB,IHC,ICC/IF,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-ANXA2 Antibody (4Q629) is a Rabbit antibody targeting ANXA2. Anti-ANXA2 Antibody (4Q629) can be used in WB,IHC,ICC/IF,FCM. |
Synonyms | PAP-IV, p36, LPC2DP36, LPC2D, Lipocortin II, LIP2PAP-IV, Chromobindin-8, CAL1H, ANXA2, ANX2L4, ANX2, Annexin II, Annexin A2 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of Annexin A2 on different cells lysates using anti-Annexin A2 antibody at 1/500 dilution. Positive control: Lane 1: Hela, Lane 2: Human kidney, Lane 3: Murine testis. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Annexin A2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Annexin A2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Annexin A2 antibody. Counter stained with hematoxylin. 5. ICC staining Annexin A2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of K562 cells with Annexin A2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
Application | |
Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:100-200; FCM: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 38 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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