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Anti-Bim Antibody (2H443)

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Catalog No. TMAC-00441

Anti-Bim Antibody (2H443) is a Rabbit antibody targeting Bim. Anti-Bim Antibody (2H443) can be used in WB,ICC,IHC,IP.

Anti-Bim Antibody (2H443)

Anti-Bim Antibody (2H443)

😃Good
Catalog No. TMAC-00441
Anti-Bim Antibody (2H443) is a Rabbit antibody targeting Bim. Anti-Bim Antibody (2H443) can be used in WB,ICC,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Bim Antibody (2H443) is a Rabbit antibody targeting Bim. Anti-Bim Antibody (2H443) can be used in WB,ICC,IHC,IP.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPro-apototic Bcl-2 family members promote cell death by neutralizing their apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1/2 phosphorylation exist on BimEL, whereas ERK1/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 22/16/13 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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