Immobilized Human ITGA5&ITGB1, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ITGA5&ITGB1 Antibody, hFc Tag with the EC50 of 16.2 ng/ml determined by ELISA.

Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P08648(ITGA5)&P05556-1(ITGB1).

Human

HEK293 Cells

VLA5A,VLA-5,integrin, α5 (fibronectin receptor, α polypeptide),integrin, alpha 5 (fibronectin receptor, alpha polypeptide),Integrin α5 β 1,Integrin alpha 5 β1,FNRA,CD49e

Phe42-Tyr995(ITGA5) acidic tail & Gln21-Asp728(ITGB1) basic tail

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Integrin alpha 5/ beta 1, also known as VLA-5, is a widely expressed non-covalent heterodimer of a 160 kDa alpha 5 and a 130 kDa beta 1 Integrin subunit.Alpha 5/ beta 1 is up‑regulated on tumor vasculature and promotes angiogenesis.