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Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi)

TargetMol | SPR
Catalog No. TMPY-02159U

Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P08648(ITGA5)&P05556-1(ITGB1).

Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi)

Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi)

TargetMol | SPR
Catalog No. TMPY-02159U
Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P08648(ITGA5)&P05556-1(ITGB1).
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Bulk & Custom
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Product Information

Biological Activity
Immobilized Human ITGA5&ITGB1, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ITGA5&ITGB1 Antibody, hFc Tag with the EC50 of 16.2 ng/ml determined by ELISA.
Description
Integrin alpha 5 beta 1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P08648(ITGA5)&P05556-1(ITGB1).
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP08648(ITGA5)&P05556-1(ITGB1)
Synonyms
VLA5A,VLA-5,integrin, α5 (fibronectin receptor, α polypeptide),integrin, alpha 5 (fibronectin receptor, alpha polypeptide),Integrin α5 β 1,Integrin alpha 5 β1,FNRA,CD49e
Construction
Phe42-Tyr995(ITGA5) acidic tail & Gln21-Asp728(ITGB1) basic tail
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight111.8 kDa (ITGA5) & 83.2 kDa (ITGB1) (Predicted); 100-140 kDa (Due to glycosylation)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Integrin alpha 5/ beta 1, also known as VLA-5, is a widely expressed non-covalent heterodimer of a 160 kDa alpha 5 and a 130 kDa beta 1 Integrin subunit.Alpha 5/ beta 1 is up‑regulated on tumor vasculature and promotes angiogenesis.

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