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Anti-CD11b Antibody (5R461)

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Catalog No. TMAB-03829

Anti-CD11b Antibody (5R461) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (5R461) can be used in IHC-P,IHC-Fr,IF,WB.

Anti-CD11b Antibody (5R461)

Anti-CD11b Antibody (5R461)

😃Good
Catalog No. TMAB-03829
Anti-CD11b Antibody (5R461) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (5R461) can be used in IHC-P,IHC-Fr,IF,WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD11b Antibody (5R461) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (5R461) can be used in IHC-P,IHC-Fr,IF,WB.
Ig Type
IgG
Clone
5R461
Reactivity
Mouse,Rat,Human
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
Tissue SpecificityPredominantly expressed in monocytes and granulocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mhuman CD11b
Antigen Species
Human
Gene Name
ITGAM
Gene ID
Protein Name
Integrin alpha-M
Uniprot ID
Function
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Chemical Properties
Molecular WeightTheoretical: 125 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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