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Anti-CD22 Antibody (9H533)

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Catalog No. TMAB-03915

Anti-CD22 Antibody (9H533) is a Rabbit antibody targeting CD22. Anti-CD22 Antibody (9H533) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-CD22 Antibody (9H533)

Anti-CD22 Antibody (9H533)

😃Good
Catalog No. TMAB-03915
Anti-CD22 Antibody (9H533) is a Rabbit antibody targeting CD22. Anti-CD22 Antibody (9H533) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD22 Antibody (9H533) is a Rabbit antibody targeting CD22. Anti-CD22 Antibody (9H533) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
9H533
Reactivity
Human
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein.
Tissue SpecificityB-lymphocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundPredicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. [provided by Alliance of Genome Resources, Nov 2021]
Antigen Details
Immunogen
A synthesized peptide: human CD22
Antigen Species
Human
Gene Name
CD22
Gene ID
933
Protein Name
B-cell receptor CD22
Uniprot ID
P20273
Function
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Chemical Properties
Molecular WeightTheoretical: 91 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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