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Bad Protein, Human, Recombinant (GST)
(Synonyms: Bcl2-L-8, BCL2L8, Bcl2-associated agonist of cell death, BBC6, BAD) Copy Product InfoSynonyms: Bcl2-L-8, BCL2L8, Bcl2-associated agonist of cell death, BBC6, BAD
Catalog No. TMPC-00075 Copy Product Info
Bad Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is Q92934.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μg | $953 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | Bad Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is Q92934. |
| Species | Human |
| Expression System | Baculovirus-Insect Cells |
| Tag | N-GST |
| Accession Number | Q92934 |
| Construction | Recombinant full length human BAD was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Protein Purity | >70% as determined by SDS-PAGE.  |
| Formulation | Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. |
| Synonyms | Bcl2-L-8, BCL2L8, Bcl2-associated agonist of cell death, BBC6, BAD |
| Research Background | Bcl-2 agonist of cell death (BAD) is a BH3-only member of the Bcl-2 family which possesses important regulatory function in apoptosis. BAD has also been shown to possess many non-apoptotic functions closely linked to cancer including regulation of glycolysis, autophagy, cell cycle progression and immune system development. Oral squamous cell carcinoma (OSCC) is a type of cancer with high morbidity and mortality rates worldwide; it also demonstrates chemotherapeutic resistance. Triterpenoid ursolic acid has been shown to exhibit various biological activities and anticancer effects in several preclinical studies. The apoptosis‑associated signaling showed that ursolic acid decreased the phosphorylation of AKT (Ser473) and B‑cell lymphoma 2 (Bcl‑2)‑associated agonist of cell death (BAD; Ser136), and the protein levels of Bcl‑2 and Bcl‑extra large (Bcl‑xL), and increased the expression of BAD and Bcl‑2‑associated X (Bax) protein in CAR cells. |
| Molecular Weight | ~47 kDa |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Bad Protein, Human, Recombinant (GST) chemical structure | Bad Protein, Human, Recombinant (GST) molecular weight
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