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Anti-PDZK1 Antibody (9U150)

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Catalog No. TMAB-10158

Anti-PDZK1 Antibody (9U150) is a Rabbit antibody targeting PDZK1. Anti-PDZK1 Antibody (9U150) can be used in IP,IHC-P,IHC-Fr,IF.

Anti-PDZK1 Antibody (9U150)

Anti-PDZK1 Antibody (9U150)

😃Good
Catalog No. TMAB-10158
Anti-PDZK1 Antibody (9U150) is a Rabbit antibody targeting PDZK1. Anti-PDZK1 Antibody (9U150) can be used in IP,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PDZK1 Antibody (9U150) is a Rabbit antibody targeting PDZK1. Anti-PDZK1 Antibody (9U150) can be used in IP,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
9U150
Reactivity
Human
Application
Recommended Dose
IP: 1:20-50; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Membrane. Associated with peripheral membranes. Localizes to the apical compartment of proximal tubular cells and to sinusoidal liver membranes.
Tissue SpecificityExpression is limited to epithelial cells. Expressed in the kidney (brush border of proximal tubule), pancreas, liver, and small intestine. Expressed at a lower level in the adrenal cortex, testis and stomach. Overexpressed in breast, renal and lung carcinomas.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundA scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins.
Antigen Details
Immunogen
A synthesized peptide: human PDZK1
Antigen Species
Human
Gene Name
PDZK1
Gene ID
Protein Name
Na(+)/H(+) exchange regulatory cofactor NHE-RF3
Uniprot ID
Function
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
Chemical Properties
Molecular WeightTheoretical: 57 kDa. Actual: 70 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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