Immobilized Human Transferrin R, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human Transferrin, His Avi Tag with the EC50 of 14.3 ng/ml determined by ELISA. (QC Test)
Immobilized Human Transferrin R, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Transferrin R Antibody, hFc Tag with the EC50 of 6.8 ng/ml determined by ELISA.
Loaded Anti-Transferrin R Antibody, hFc Tag on ProA-Biosensor can bind Human Transferrin R, His Tag with an affinity constant of 0.65 nM as determined in BLI assay (Gator® Prime).

Transferrin Receptor/TFRC Dimer Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P02786.

Human

HEK293 Cells

TRFR,transferrin receptor,TR,TFR1,TFR,T9,p90,CD71

Cys89-Phe760

> 90% as determined by Bis-Tris PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.