IgE Fc Protein, Human, Recombinant (His) V2

Name: IgE Fc Protein, Human, Recombinant (His) V2
Brand: TargetMol
SKU: TMPY-05072U
Rating: 4.5 (1 reviews)

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Catalog No. TMPY-05072U Copy Product Info

IgE Fc Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P01854-1.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$86	7-10 days	7-10 days
20 µg	$139	7-10 days	7-10 days
50 µg	$269	7-10 days	7-10 days
100 µg	$451	7-10 days	7-10 days
200 µg	$743	7-10 days	7-10 days
500 µg	$1,430	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 2.5 ng/ml determined by ELISA. (QC Test) Immobilized Human IgE, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Omalizumab, hFc Tag with the EC50 of 5.0 ng/ml determined by ELISA.
Description	IgE Fc Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P01854-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P01854-1
Construction	Ser106-Lys428
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 0.1 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Research Background	Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

Chemical Properties

Molecular Weight

37.49 kDa (Predicted); 45-60 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.