AMSH/STAMBP Protein, Human, Recombinant (His)

Catalog No. TMPC-00068 Copy Product Info

AMSH/STAMBP Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is O95630.

AMSH/STAMBP Protein, Human, Recombinant (His)

Catalog No. TMPC-00068

Copy Product Info

AMSH/STAMBP Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is O95630.

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10 μg	$1,280	Inquiry	Inquiry

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	The specific activity of AMSH was determined to be 9-12 nmol /min/mg by a ubiquitin-based proluciferin assay.
Description	AMSH/STAMBP Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is O95630.
Species	Human
Expression System	Baculovirus-Insect Cells
Tag	N-His
Accession Number	O95630
Synonyms	STAMBP,STAM-binding protein,AMSH
Construction	Recombinant full length human AMSH was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.
Protein Purity	>70% as determined by SDS-PAGE.
Molecular Weight	~54 kDa
Formulation	Supplied as sterile 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Research Background	STAMBP (STAM Binding Protein) is a Protein Coding gene. The STAMBP gene, located on 2p13.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. STAMBP is a JAMM-family deubiquitinating enzyme containing the microtubule-interacting/transport domain and STAM-binding domain. STAMBP is widely expressed in the thyroid, brain, and other tissues. Microcephaly-capillary malformation syndrome is a congenital and neurodevelopmental disorder caused by biallelic mutations in the STAMBP gene. Among its related pathways are the EGF/EGFR Signaling Pathway and Metabolism of proteins.