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SB 258585

Name: SB 258585
Brand: TargetMol
SKU: T23318L
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T23318LCas No. 209480-63-7

SB 258585 is a selective 5-HT6 receptor antagonist.SB 258585 has a high affinity for individual receptor populations in cell lines with human recombinant 5-HT6 receptors.SB 258585 can be used to label both recombinant and natural 5-HT6 receptors, and can be used to assay cognitive enhancement and antipsychotic activity.

SB 258585

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Purity: 99.77%

Catalog No. T23318LCas No. 209480-63-7

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$40	-	In Stock
10 mg	$68	-	In Stock
25 mg	$123	-	In Stock
50 mg	$217	-	In Stock
100 mg	$310	-	In Stock
200 mg	$436	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.77%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	487.36
Formula	C₁₈H₂₂IN₃O₃S
Cas No.	209480-63-7
Smiles	O=S(NC1=CC=C(C(N2CCN(CC2)C)=C1)OC)(C3=CC=C(C=C3)I)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (102.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0519 mL	10.2594 mL	20.5187 mL	102.5936 mL
5 mM	0.4104 mL	2.0519 mL	4.1037 mL	20.5187 mL
10 mM	0.2052 mL	1.0259 mL	2.0519 mL	10.2594 mL
20 mM	0.1026 mL	0.5130 mL	1.0259 mL	5.1297 mL
50 mM	0.0410 mL	0.2052 mL	0.4104 mL	2.0519 mL
100 mM	0.0205 mL	0.1026 mL	0.2052 mL	1.0259 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc