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Anti-GMNN Antibody (6Z839)
😃Good
Catalog No. TMAH-00498
Alias Geminin
Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF.
Anti-GMNN Antibody (6Z839)
Anti-GMNN Antibody (6Z839)
😃Good
Catalog No. TMAH-00498Alias Geminin
Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF. |
| Synonyms | Geminin |
| Ig Type | Rabbit IgG |
| Clone | 6Z839 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of Hela Cells with TMAH-00498 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| Application | |
| Recommended Dose | IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Geminin |
| Antigen Species | Human |
| Gene Name | GMNN |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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