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Anti-GMNN Antibody (6Z839) (Synonyms: Geminin)

Catalog No. TMAH-00498 Copy Product Info
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Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF.

Anti-GMNN Antibody (6Z839)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00498
Synonyms Geminin

Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF.

Anti-GMNN Antibody
(6Z839)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF.
SynonymsGeminin
Ig Type
Rabbit IgG
Clone
6Z839
Reactivity
Human
Verified Activity
Immunofluorescence staining of Hela Cells with TMAH-00498 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Application
Recommended Dose
IF:1:20-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm. Nucleus.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundInhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Geminin
Antigen Species
Human
Gene Name
GMNN
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cancer
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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