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Anti-Crotonyl-Histone H2B (Lys15/Lys16/Lys20) Antibody (9A793) is a Rabbit antibody targeting Crotonyl-Histone H2B (Lys15/Lys16/Lys20). Anti-Crotonyl-Histone H2B (Lys15/Lys16/Lys20) Antibody (9A793) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-Crotonyl-Histone H2B (Lys15/Lys16/Lys20) Antibody (9A793) is a Rabbit antibody targeting Crotonyl-Histone H2B (Lys15/Lys16/Lys20). Anti-Crotonyl-Histone H2B (Lys15/Lys16/Lys20) Antibody (9A793) can be used in WB. |
| Ig Type | IgG |
| Clone | 9A793 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated Synthesised acetylpeptide: human Histone H2B around the Crotonyl site of Lys15 / Lys16 / Lys20 |
| Antigen Species | Human |
| Gene Name | H2BC3 |
| Gene ID | |
| Protein Name | Histone H2B type 1-B |
| Uniprot ID | |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Molecular Weight | Theoretical: 14 kDa. Actual: 14 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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