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Anti-IKB beta Antibody (8N845)
😃Good
Catalog No. TMAB-07572
Anti-IKB beta Antibody (8N845) is a Rabbit antibody targeting IKB beta. Anti-IKB beta Antibody (8N845) can be used in WB.
Anti-IKB beta Antibody (8N845)
Anti-IKB beta Antibody (8N845)
😃Good
Catalog No. TMAB-07572
Anti-IKB beta Antibody (8N845) is a Rabbit antibody targeting IKB beta. Anti-IKB beta Antibody (8N845) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IKB beta Antibody (8N845) is a Rabbit antibody targeting IKB beta. Anti-IKB beta Antibody (8N845) can be used in WB. |
| Ig Type | IgG |
| Clone | 8N845 |
| Reactivity | Human (predicted:Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Expressed in all tissues examined. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS, Glycerol, BSA. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]. |
| Immunogen | KLH conjugated synthetic peptide: human IKB beta |
| Antigen Species | Human |
| Gene Name | NFKBIB |
| Gene ID | |
| Protein Name | NF-kappa-B inhibitor beta |
| Uniprot ID | |
| Function | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
| Molecular Weight | Theoretical: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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