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Synonyms: ALK-7, ALK7, ALK 7, ACVRLK-7, ACVRLK7, ACVRLK 7, ACVR1C, ACTR-IC, Activin receptor type-1C, activin A receptor, type IC


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $74 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human ALK-7, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ALK-7 Antibody, hFc Tag with the EC50 of 3.15 ng/ml determined by ELISA (QC Test). Anti-ALK-7 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human ALK-7, His Tag with an affinity constant of 0.67 nM as determined in SPR assay (Biacore T200). |
| Description | ALK-7 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q8NER5-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q8NER5-1 |
| Construction | Glu21-Glu113 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 8% trehalose (pH 7.5) |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | ALK-7, ALK7, ALK 7, ACVRLK-7, ACVRLK7, ACVRLK 7, ACVR1C, ACTR-IC, Activin receptor type-1C, activin A receptor, type IC |
| Research Background | Arterial stiffness is an important feature of diabetic macrovascular complications. Activin receptor-like kinase 7 (ALK7), a member of type I transforming growth factor-β (TGF-β) receptors, is correlated with pathogenic risks of type 2 diabetes mellitus and cardiovascular diseases and may be involved in cardiovascular remodeling. |
| Molecular Weight | 11.11 kDa (Predicted); 20-40 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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