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Anti-CD40 Antibody (2Z619)
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Catalog No. TMAB-03983
Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB.
Anti-CD40 Antibody (2Z619)
Anti-CD40 Antibody (2Z619)
Copy Product Info😃Good
Catalog No. TMAB-03983
Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB. |
| Ig Type | IgG |
| Clone | 2Z619 |
| Reactivity | Human |
| Verified Activity | 1. 25 μg total protein per lane of various lysates (see on figure) probed with CD40 monoclonal antibody, unconjugated (TMAB-03983) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. 2. 25 μg total protein per lane of various lysates (see on figure) probed with CD40 monoclonal antibody, unconjugated (TMAB-03983) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. |
| Tissue Specificity | B-cells and in primary carcinomas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS, Glycerol, BSA. |
| Concentration | 1mg/ml |
| Research Background | Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | KLH conjugated synthetic peptide: human CD40 |
| Antigen Species | Human |
| Gene Name | Cd40 |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 5 |
| Uniprot ID |
| Molecular Weight | Theoretical: 30 kDa. Actual: 44-50 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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