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Anti-CD40 Antibody (2Z619)

Catalog No. TMAB-03983 Copy Product Info
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Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB.

Anti-CD40 Antibody (2Z619)

Copy Product Info
🥰Excellent
Catalog No. TMAB-03983

Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB.

Anti-CD40 Antibody
(2Z619)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB.
Ig Type
IgG
Clone
2Z619
Reactivity
Human
Verified Activity
1. 25 μg total protein per lane of various lysates (see on figure) probed with CD40 monoclonal antibody, unconjugated (TMAB-03983) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. 25 μg total protein per lane of various lysates (see on figure) probed with CD40 monoclonal antibody, unconjugated (TMAB-03983) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted.
Tissue SpecificityB-cells and in primary carcinomas.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPBS, Glycerol, BSA.
Concentration1mg/ml
Research BackgroundPredicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CD40
Antigen Species
Human
Gene Name
Cd40
Gene ID
958
Protein Name
Tumor necrosis factor receptor superfamily member 5
Uniprot ID
P25942
Chemical Properties
Molecular WeightTheoretical: 30 kDa. Actual: 44-50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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