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Anti-NME1/NM23A Antibody (1C377)

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Catalog No. TMAB-09533

Anti-NME1/NM23A Antibody (1C377) is a Rabbit antibody targeting NME1/NM23A. Anti-NME1/NM23A Antibody (1C377) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-NME1/NM23A Antibody (1C377)

Anti-NME1/NM23A Antibody (1C377)

😃Good
Catalog No. TMAB-09533
Anti-NME1/NM23A Antibody (1C377) is a Rabbit antibody targeting NME1/NM23A. Anti-NME1/NM23A Antibody (1C377) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-NME1/NM23A Antibody (1C377) is a Rabbit antibody targeting NME1/NM23A. Anti-NME1/NM23A Antibody (1C377) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1C377
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Note=Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
Tissue SpecificityIsoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMajor role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities.
Antigen Details
Immunogen
A synthesized peptide: human NDK A
Antigen Species
Human
Gene Name
NME1
Gene ID
Protein Name
Nucleoside diphosphate kinase A
Uniprot ID
Function
Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
Chemical Properties
Molecular WeightTheoretical: 17 kDa. Actual: 17 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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