Immobilized Human PD-1, hFc Tag at 1 μg/ml (100 μl/Well). Dose response curve for Human PD-L1, mFc Tag with the EC50 of 0.1 μg/ml determined by ELISA.
Human PD-1, hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated Human PD-L2, His-Avi Tag with an affinity constant of 0.344 μM as determined in SPR assay (Biacore T200).

PD-1 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q15116-1.

Human

HEK293 Cells

SLEB2,programmed cell death 1,PD-1,PD1,hSLE1,hPD-l,hPD-1,CD279

Leu25-Gln167

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.