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Synonyms: T1, Mitochondrial 3-oxoacyl-CoA thiolase, mitochondrial, EC 2.3.1.16, Beta-ketothiolase, Acetyl-CoA acyltransferase, 3-ketoacyl-CoA thiolase
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-ACAA2 Antibody (7X361) is an antibody targeting ACAA2. Anti-ACAA2 Antibody (7X361) can be used in ELISA,IF,IHC,WB. |
| Synonyms | T1, Mitochondrial 3-oxoacyl-CoA thiolase, mitochondrial, EC 2.3.1.16, Beta-ketothiolase, Acetyl-CoA acyltransferase, 3-ketoacyl-CoA thiolase |
| Ig Type | Rabbit IgG |
| Clone | 7X361 |
| Reactivity | Human, Mouse |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IHC:1:50-1:200; IF:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Mitochondrion. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation. Abolishes BNIP3-mediated apoptosis and mitochondrial damage. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ACAA2 |
| Antigen Species | Human |
| Gene Name | ACAA2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cardiovascular, Tags & Cell Markers, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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